• What are generics and should we be afraid of them

    Generics are analogs of drugs that have an equivalent composition and therapeutic properties in comparison with the originals, the term of which patent protection has expired. Generics are produced under other names, but in strict compliance with established regulations, quality standards and safety. The active ingredients and dosages of the active ingredients of generics fully correspond to the brand-name drugs. Differences may lie in the composition of inactive ingredients, which affects the color, size, shape and taste of the drug. The effects on the body, that is, the speed of achievement and duration of preservation of a certain concentration of active substances in the blood, are the same for generics and originals. The prices for generics are usually several times lower than for patented drugs. This is due to the fact that the cost of the original drug includes research, development and advertising campaigns, and manufacturers have no such costs.In addition, during the period of the patent protection, the manufacturer of the original products has the exclusive right to sell. At the end of this period, generics can produce any pharmaceutical company, which creates market competition and causes low prices. The bad reputation of generics is often created by medical representatives of pharmaceutical companies producing proprietary drugs. Insufficient knowledge, poor efficiency, high frequency of side effects, lack of biological, pharmacological and therapeutic equivalence - these and other arguments not confirmed by scientific research lead doctors to believe that prescribing generics is not the best idea. However, doctors prescribe medications with an eye to the patient’s financial situation, therefore, with obviously low incomes, they are still leaning in favor of the generic. However, many drugs produced in Russia since Soviet times and developed in recent decades, are generics, copied from foreign branded counterparts. Among them are famous,widely used in clinical practice, drugs, in particular, "Diclofenac", "Fluconazole", "Pancreatin", "Loperamide", "Furazolidone", "Ibuprofen", "Paracetamol", "Metronidazole", "Azithromycin", "Enalapril " etc. Today, when registering generics, biological and therapeutic equivalence tests are required. This gives some reason not to doubt their effectiveness. Research results are voiced at medical conferences and published in specialized journals. Generics produce serious world-famous pharmaceutical companies that value their name and reputation, including the developers of original drugs. While branded drugs are often counterfeited, this happens less frequently with generics, because it is economically unprofitable. In general, the danger of generics is greatly exaggerated, because virtually every drug has generic counterparts, giving doctors and patients the right to choose.

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