Yersinia pestis - The Plague : Microbiology Lectures
What Is Yersinia Pestis?
Yersinia pestisis a type of disease-causing bacteria that causes all three forms of plague — bubonic, septicemic, and pneumonic.
is widely known as the disease behind the devastating "Black Death" of the European Middle Ages that killed up to 60 percent of the European population, according to the Centers for Disease Control and Prevention (CDC).
The name of the bacteria comes from doctor and bacteriologist Alexandre Yersin, who discovered thatY. pestiscauses plague in the mid-1890s while studying a plague epidemic in Hong Kong.
NumerousYersiniaspecies are known to exist today, but only two species besidesY. pestis—Y. pseudotuberculosisandY. enterocolitica— cause disease in people, according to a 2003 report in theAmerican Journal of Clinical Pathology.
Yersinia Pestisin Rodents and Fleas
Yersinia pestisis an obligate parasite, meaning that it cannot reproduce without a host.
Rodents are the primary hosts of the bacteria, which is spread through fleas.
When a flea feeds on an infected rodent, such as a rat, it swallowsY. pestis.
The bacteria multiplies in the gut of the flea and produces an enzyme that clots the blood the flea ingests, preventing the blood from moving past the flea's esophagus.
The flea is unable to fully ingest blood, so every time it tries to feed on an animal, it ends up regurgitating the blood — which has become newly infected withY. pestis— back into the animal, infecting it.
Rodents and fleas generally serve as long-term reservoirs ofY. pestis,because the bacteria generally can't circulate quickly enough in these animals to cause massive die-offs.
But sometimes the infection rate can surge, killing many rodents — in the southwestern United States, this spike is more likely to occur in cooler summers that follow wet winters, the CDC notes.
When the infected fleas' food source dies off in this way, the hungry insects seek out new animals to bite — particularly cats, dogs, and people.
Transmission to People
When people are infected with plague bacteria, it's usually through bites from fleas.
IfY. pestistravels to the lymphatic system from the bite wound, it causes bubonic plague. If it travels to the bloodstream, it causes septicemic plague.
People can also catch bubonic and septicemic plague by handling the tissues or bodily fluids of infected animals.
For example, you can become infected if you accidentally cut yourself while skinning a freshly caught rabbit or other animal.
Pneumonic plague, which develops whenY. pestisinfects the lungs, can spread to people through infected droplets.
This means that if a person or pet with pneumonic plague coughs or sneezes into the air, you can catch the bacteria — and get pneumonic plague — if you inhale those infected droplets.
Yersinia pestishas caused three major plague pandemics in recorded history:
- The Justinian Plague, which began in 541 A.D.
- The Black Death, which began in 1334
- The Modern Plague, which began in 1860
ThoughY. pestisstill causes plague today, the strain of bacteria is different from the (probably extinct) strain that caused the Black Death, according to research published in 2011 in theProceedings of the National Academy of Sciences.
What's more, theY. pestisstrain behind the Black Death is different from the strain behind the Justinian Plague, which probably also went extinct before the second pandemic took place, according to a 2014 study inThe Lancet Infectious Diseases.
Other recent research has begun to establish when the bacteria first evolved into existence.
A 2015 study in the journalCellreported thatY. pestishas affected people for as long as 5,000 years.
Also in 2015, a study in theJournal of Medical Entomologyreported the discovery of a piece of amber encasing a 20-million-year-old flea that had bacteria attached to it; that bacteria resemblesY. pestisin appearance and may be related to it.
Video: Yersinia pestis -animated quick review
Crispy Coconut Shrimp
Your December Sex Horoscope: More Intimacy Equals Better Orgasms
Fixer Upper Houses Have to Meet These 3 Criteria to Be Considered for the Show
Chic And Awesome DIY Bag Tassels
Riding Cancer’s Emotional Roller Coaster
Ipratropium Nasal Reviews
7 Ways to Boost Metabolism When You Have Hypothyroidism
Christy Turlington Releases New Maternity Line Inspiring Short Film
30 Ways to Blast Fat, Fast
How to Defend Your Property Against an Intruder
How to Start a Volunteer Organization
Signs You May Have Above-Average Intelligence